CACNA1I Antikörper

Produktnummer ABIN265034

Produktdetails anti-CACNA1I Antikörper

Target: CACNA1I (Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA1I Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to CACNA1I.

Aufreinigung: Purified

Immunogen: Synthetic peptide derived from the rat alpha1I calcium channel conjugated to KLH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu CACNA1I

Target: CACNA1I (Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I))

Andere Bezeichnung: CACNA1I (CACNA1I Produkte)

Synonyme: CACNA1L antikoerper, Ca(V)3.3 antikoerper, Cav3.3 antikoerper, ca(v)3.3 antikoerper, si:ch211-51h13.1 antikoerper, Ca(v)3.3 antikoerper, calcium voltage-gated channel subunit alpha1 I antikoerper, voltage-dependent T-type calcium channel subunit alpha-1I antikoerper, calcium channel, voltage-dependent, alpha 1I subunit antikoerper, calcium channel, voltage-dependent, T type, alpha 1I subunit antikoerper, CACNA1I antikoerper, LOC100555412 antikoerper, Cacna1i antikoerper, cacna1i antikoerper

Hintergrund: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. Using co-transfection techniques we investigated the functional effects of each of the gamma subunits on the biophysics of the T-type VSCC encoded by the alpha(1I) subunit. This revealed a substantially slowed rate of deactivation in the presence of gamma(2). In contrast, there was no significant corresponding effect of either gamma(3) or gamma(4) on alpha(1I) subunit-mediated currents.(2)Synonyms: Ca(v)3.3, Cav3.3, KIAA1120, Voltage-dependent T-type calcium channel subunit alpha-1I, Voltage-gated calcium channel subunit alpha Cav3.3

Gen-ID: 8911

NCBI Accession: NP_001003406

UniProt: Q9P0X4