WWTR1 Antikörper (WW Domain Containing Transcription Regulator 1)

Details for Product anti-WWTR1 Antibody No. ABIN258561
Antigen
  • WWTR1
  • TAZ
  • 2310058J06Rik
  • 2610021I22Rik
  • C78399
  • Taz
  • WW domain containing transcription regulator 1 L homeolog
  • WW domain containing transcription regulator 1
  • wwtr1.L
  • wwtr1
  • WWTR1
  • Wwtr1
Reaktivität
Human, Maus, Ratte (Rattus)
65
21
9
3
2
1
1
1
Wirt
Kaninchen
52
14
Klonalität
Polyklonal
Konjugat
Dieser WWTR1 Antikörper ist unkonjugiert
3
2
2
2
2
2
2
2
2
2
2
1
Applikation
Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Simple Western (SimWes), Western Blotting (WB)
52
20
11
6
5
3
2
1
1
Optionen
Immunogen Synthetic peptides made to the human TAZ protein. These peptides were selected for the lack of homology to YAP protein. [UniProt# Q9GZV5]
Reinigung Immunogen affinity purified
Plasmids, Primers & others Plasmide, Primers & weitere WWTR1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung TAZ/WWTR1 (WWTR1 Antibody Abstract)
Hintergrund Gene Symbol: WWTR1
Gen-ID 25937
UniProt Q9GZV5
Pathways Regulation of Lipid Metabolism by PPARalpha
Applikations-hinweise Western Blot 1:1000-1:5000, Simple Western 1:100, Chromatin Immunoprecipitation, Immunocytochemistry/Immunofluorescence 1:50-1:200, Immunoprecipitation 1:100, Immunohistochemistry-ParaffinThis TAZ Antibody is useful for Immunocytochemistry/Immunofluorescence, Immunoprecipitation and Western blot. Use in chromatin immunoprecipitation and Immunohistochemistry-paraffin reported in scientific literature (PMID 25587023). In Simple Western only 10 - 15 μL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1.0 mg/mL
Buffer PBS, 15 % glycerol
Buffer contains: 0.02 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze-thaw cycles
Lagerung -80 °C,-20 °C
Informationen zur Lagerung Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibody (ABIN258561) Detection of ABIN258561 protein using ABIN258561 on HEK 293 cell lysate.
Simple Western (SimWes) image for anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibody (ABIN258561) Simple Western: TAZ/WWTR1 Antibody [ABIN2585619] - Simple Western lane view shows a s...
Western Blotting (WB) image for anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibody (ABIN258561) Western Blot: TAZ/WWTR1 Antibody [ABIN2585619] - WB analysis of Taz in HEK293T cell l...
Immunofluorescence (IF) image for anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibody (ABIN258561) Immunocytochemistry/Immunofluorescence: TAZ/WWTR1 Antibody [ABIN2585619] - Detection ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibody (ABIN258561) Immunohistochemistry-Paraffin: TAZ/WWTR1 Antibody - IHC analysis of formalin fixed p...
Produkt verwendet in: Hwang, Kim, Kim, Il Park, Oh, Moon, Byun, Jeong, Kim, Yaffe, Hwang, Hong: "TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression." in: Nature communications, Vol. 10, Issue 1, pp. 421, 2019 (PubMed). Von den Autoren verwendete Methode: Chromatin Immunoprecipitation (ChIP) (Probematerial (Species): Mouse (Murine)).

Wu, Deng, Wang, Zhao, Wang, Rao, Xu, Zhou, Choi, Rizvi, Remke, Rubin, Johnson, Carroll, Stemmer-Rachamimov, Wu, Zheng, Xin, Ratner, Lu: "Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis." in: Cancer cell, Vol. 33, Issue 2, pp. 292-308.e7, 2018 (PubMed).

Yu, Huo, Liu, Deng, Szymanski, Li, Luo, Hong, Lin, Wang: "PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ." in: Cell stem cell, Vol. 23, Issue 2, pp. 193-209.e5, 2018 (PubMed).

Deng, Wu, Bai, Zhao, Wang, Wang, Xu, Sakabe, Zhou, Xin, Lu: "A reciprocal regulatory loop between TAZ/YAP and G-protein Gαs regulates Schwann cell proliferation and myelination." in: Nature communications, Vol. 8, pp. 15161, 2017 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human).

Xiang, Gilkes, Hu, Takano, Luo, Lu, Bullen, Samanta, Liang, Semenza: "Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype." in: Oncotarget, Vol. 5, Issue 24, pp. 12509-27, 2015 (PubMed). (Probematerial (Species): Human). Weitere Details: Immunocytochemistry,Western Blotting,Immunohistochemistry (Paraffin-embedded Sections),Immunoprecipitation,Chromatin Immunoprecipitation,Immunofluorescence

Xiang, Gilkes, Hu, Luo, Bullen, Liang, Semenza: "HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells." in: Oncotarget, Vol. 6, Issue 14, pp. 11768-78, 2015 (PubMed). (Probematerial (Species): Human). Weitere Details: Western Blotting,Chromatin Immunoprecipitation,Immunoprecipitation

de Cristofaro, Di Palma, Ferraro, Corrado, Lucci, Franco, Fusco, Zannini: "TAZ/WWTR1 is overexpressed in papillary thyroid carcinoma." in: European journal of cancer (Oxford, England : 1990), Vol. 47, Issue 6, pp. 926-33, 2011 (PubMed). (Probematerial (Species): Rat (Rattus)). Weitere Details: Western Blotting

Strakova, Reed, Ihnatovych: "Human transcriptional coactivator with PDZ-binding motif (TAZ) is downregulated during decidualization." in: Biology of reproduction, Vol. 82, Issue 6, pp. 1112-8, 2010 (PubMed).

Varelas, Miller, Sopko, Song, Gregorieff, Fellouse, Sakuma, Pawson, Hunziker, McNeill, Wrana, Attisano: "The Hippo pathway regulates Wnt/beta-catenin signaling." in: Developmental cell, Vol. 18, Issue 4, pp. 579-91, 2010 (PubMed). (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

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