FBXO32 Antikörper
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- Target Alle FBXO32 Antikörper anzeigen
- FBXO32 (F-Box Protein 32 (FBXO32))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FBXO32 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide of human FBXO32
- Isotyp
- IgG
- Top Product
- Discover our top product FBXO32 Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:1000
- Kommentare
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Specifically expressed in cardiac and skeletal muscle
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- FBXO32 (F-Box Protein 32 (FBXO32))
- Andere Bezeichnung
- FBXO32 (FBXO32 Produkte)
- Synonyme
- MGC56479 antikoerper, zgc:56479 antikoerper, Fbx32 antikoerper, MAFbx antikoerper, 4833442G10Rik antikoerper, AI430017 antikoerper, ATROGIN1 antikoerper, Gm20361 antikoerper, Atrogin1 antikoerper, F-box protein 32 antikoerper, fbxo32 antikoerper, FBXO32 antikoerper, Fbxo32 antikoerper
- Hintergrund
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molekulargewicht
- 41.637 kDa
- Gen-ID
- 114907
- UniProt
- Q969P5
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