Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 20-37) Antikörper

Details zu Produkt Nr. ABIN252469, Anbieter: Anmelden zum Anzeigen
Antigen
  • OCIF
  • OPG
  • TR1
  • Opg
  • ocif
  • opg
  • tr1
  • TNF receptor superfamily member 11b
  • tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
  • TNF receptor superfamily member 11B
  • tumor necrosis factor receptor superfamily member 11b S homeolog
  • tumor necrosis factor receptor superfamily, member 11b
  • TNFRSF11B
  • Tnfrsf11b
  • tnfrsf11b.S
Epitop
AA 20-37
26
14
10
9
9
9
8
5
4
3
3
2
2
2
1
1
1
1
1
1
Reaktivität
Human, Ratte (Rattus)
175
40
25
4
3
3
3
1
1
1
Wirt
Maus
96
69
8
2
1
Klonalität (Klon)
Monoklonal ()
Konjugat
Unkonjugiert
11
5
5
5
5
4
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
157
85
72
48
42
35
28
17
12
12
3
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen A peptide corresponding to the amino acids 20-37 TQETFPPKYLHYDEETSH of human Osteoprotegerin was used as immunogen for this antibody.
Klon 98A1071
Isotyp IgG1 kappa
Spezifität The Osteoprotegerin antibody, clone 98A1071, detects all forms of Osteoprotegerin including monomeric, dimeric and Osteoprotegerin bound to RANKL (Vandooren, 2008) as well as Osteoprotegerin bound to TRAIL (Sandra, 2006).
Reinigung Protein G purified
Andere Bezeichnung Osteoprotegerin/TNFRSF11B (TNFRSF11B Antibody Abstract)
Hintergrund Gene Symbol: TNFRSF11B
Gen-ID 4982
UniProt O00300
Applikationshinweise Western Blot 1 μg/mL, Flow Cytometry, Immunohistochemistry 1:20-1:1000, Immunocytochemistry/Immunofluorescence 1:20-1:1000, Immunoprecipitation 1:20-1:1000, Immunohistochemistry-Paraffin 1:20-1:1000, Immunohistochemistry-Frozen 1:20-1:1000, CyTOF-readyThis antibody is useful in Flow Cytometry: 0.2-1 μg/10^6 cells Immunocytochemistry/Immunofluorescence: see Sandra 2006 Immunohistochemistry (frozen): see Boumans 2012 for details. Immunoprecipitation: see Sandra 2006
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.05 % Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze-thaw cycles
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 20-37) antibody (ABIN252469) Western blot analysis for OPG with IMG-103A antibody against Daudi cell lysate. Daudi...
Flow Cytometry (FACS) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 20-37) antibody (ABIN252469) Flow Cytometry: Osteoprotegerin/TNFRSF11B Antibody (98A1071) [ABIN2524695] - Intracel...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 20-37) antibody (ABIN252469) Immunohistochemistry-Paraffin: Osteoprotegerin/TNFRSF11B Antibody (98A1071) [ABIN2524...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 20-37) antibody (ABIN252469) Immunohistochemistry-Paraffin: Osteoprotegerin/TNFRSF11B Antibody (98A1071) [ABIN2524...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 20-37) antibody (ABIN252469) Immunohistochemistry-Paraffin: Osteoprotegerin/TNFRSF11B Antibody (98A1071) [ABIN2524...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 20-37) antibody (ABIN252469) Immunohistochemistry-Paraffin: Osteoprotegerin/TNFRSF11B Antibody (98A1071) - IHC an...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 20-37) antibody (ABIN252469) Immunocytochemistry/Immunofluorescence: Osteoprotegerin/TNFRSF11B Antibody (98A1071) ...
Produkt verwendet in: Stanisławowski, Wiśniewski, Guzek, Wierzbicki, Adrych, Smoczyński, Sworczak, Celiński, Kmieć: "Influence of receptor activator of nuclear factor kappa B ligand, osteoprotegerin and interleukin-33 on bone metabolism in patients with long-standing ulcerative colitis." in: Journal of Crohn's & colitis, Vol. 8, Issue 8, pp. 802-10, 2014 (PubMed). (Probematerial (Species): Human). Weitere Details: Immunohistochemistry (Frozen Sections)

Larson, Zhang, Dumpit, Coleman, Lakely, Roudier, Higano, True, Lange, Montgomery, Corey, Nelson, Vessella, Morrissey: "Characterization of osteoblastic and osteolytic proteins in prostate cancer bone metastases." in: The Prostate, Vol. 73, Issue 9, pp. 932-40, 2013 (PubMed).

Witasp, Carrero, Hammarqvist, Qureshi, Heimbürger, Schalling, Lindholm, Nordfors, Stenvinkel: "Expression of osteoprotegerin in human fat tissue; implications for chronic kidney disease." in: European journal of clinical investigation, Vol. 41, Issue 5, pp. 498-506, 2011 (PubMed). (Probematerial (Species): Human).

Boumans, Thurlings, Yeo, Scheel-Toellner, Vos, Gerlag, Tak: "Rituximab abrogates joint destruction in rheumatoid arthritis by inhibiting osteoclastogenesis." in: Annals of the rheumatic diseases, Vol. 71, Issue 1, pp. 108-13, 2011 (PubMed).

Tomlins, Storey: "Cutaneous HPV5 E6 causes increased expression of Osteoprotegerin and Interleukin 6 which contribute to evasion of UV-induced apoptosis." in: Carcinogenesis, Vol. 31, Issue 12, pp. 2155-64, 2010 (PubMed). Weitere Details: Western Blotting

Pohjolainen, Taskinen, Soini, Rysä, Ilves, Juvonen, Ruskoaho, Leskinen, Satta: "Noncollagenous bone matrix proteins as a part of calcific aortic valve disease regulation." in: Human pathology, Vol. 39, Issue 11, pp. 1695-701, 2009 (PubMed).

Vandooren, Cantaert, Noordenbos, Tak, Baeten: "The abundant synovial expression of the RANK/RANKL/Osteoprotegerin system in peripheral spondylarthritis is partially disconnected from inflammation." in: Arthritis and rheumatism, Vol. 58, Issue 3, pp. 718-29, 2008 (PubMed).

Waterman, Cross, Lippitt, Cross, Rehman, Holen, Hamdy, Eaton: "The antibody MAB8051 directed against osteoprotegerin detects carbonic anhydrase II: implications for association studies with human cancers." in: International journal of cancer, Vol. 121, Issue 9, pp. 1958-66, 2007 (PubMed).

Sandra, Hendarmin, Nakamura: "Osteoprotegerin (OPG) binds with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): suppression of TRAIL-induced apoptosis in ameloblastomas." in: Oral oncology, Vol. 42, Issue 4, pp. 415-20, 2006 (PubMed).

Pettit, Walsh, Manning, Goldring, Gravallese: "RANKL protein is expressed at the pannus-bone interface at sites of articular bone erosion in rheumatoid arthritis." in: Rheumatology (Oxford, England), Vol. 45, Issue 9, pp. 1068-76, 2006 (PubMed).

Moschen, Kaser, Enrich, Ludwiczek, Gabriel, Obrist, Wolf, Tilg: "The RANKL/OPG system is activated in inflammatory bowel disease and relates to the state of bone loss." in: Gut, Vol. 54, Issue 4, pp. 479-87, 2005 (PubMed). Weitere Details: Immunohistochemistry (Paraffin-embedded Sections)

Sandra, Hendarmin, Kukita, Nakao, Nakamura, Nakamura: "Ameloblastoma induces osteoclastogenesis: a possible role of ameloblastoma in expanding in the bone." in: Oral oncology, Vol. 41, Issue 6, pp. 637-44, 2005 (PubMed). (Probematerial (Species): Human). Weitere Details: ELISA

Moran, McCann, Karan, Norman, Ketheesan, Golledge: "Association of osteoprotegerin with human abdominal aortic aneurysm progression." in: Circulation, Vol. 111, Issue 23, pp. 3119-25, 2005 (PubMed). Weitere Details: Western Blotting,Immunohistochemistry (Paraffin-embedded Sections)

Moschen, Kaser, Stadlmann, Millonig, Kaser, Mühllechner, Habior, Graziadei, Vogel, Tilg: "The RANKL/OPG system and bone mineral density in patients with chronic liver disease." in: Journal of hepatology, Vol. 43, Issue 6, pp. 973-83, 2005 (PubMed).

Gaudio, Lasco, Morabito, Atteritano, Vergara, Catalano, Fries, Trifiletti, Frisina: "Hepatic osteodystrophy: does the osteoprotegerin/receptor activator of nuclear factor-kB ligand system play a role?" in: Journal of endocrinological investigation, Vol. 28, Issue 8, pp. 677-82, 2005 (PubMed). Weitere Details: Immunohistochemistry (Paraffin-embedded Sections)

Pettersen, Bakkelund, Smedsrød, Sveinbjørnsson: "Osteoprotegerin is expressed in colon carcinoma cells." in: Anticancer research, Vol. 25, Issue 6B, pp. 3809-16, 2005 (PubMed).

Golledge, McCann, Mangan, Lam, Karan: "Osteoprotegerin and osteopontin are expressed at high concentrations within symptomatic carotid atherosclerosis." in: Stroke, Vol. 35, Issue 7, pp. 1636-41, 2004 (PubMed).

Vidal, van den Broek, Lorget, Donnet-Hughes: "Osteoprotegerin in human milk: a potential role in the regulation of bone metabolism and immune development." in: Pediatric research, Vol. 55, Issue 6, pp. 1001-8, 2004 (PubMed).

Vidal, Serrant, Schlosser, van den Broek, Lorget, Donnet-Hughes: "Osteoprotegerin production by human intestinal epithelial cells: a potential regulator of mucosal immune responses." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 287, Issue 4, pp. G836-44, 2004 (PubMed).

Standal, Seidel, Hjertner, Plesner, Sanderson, Waage, Borset, Sundan: "Osteoprotegerin is bound, internalized, and degraded by multiple myeloma cells." in: Blood, Vol. 100, Issue 8, pp. 3002-7, 2002 (PubMed). Weitere Details: Immunohistochemistry (Paraffin-embedded Sections)

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