RPS6KA1 Antikörper (C-Term) (FITC)

Produktnummer ABIN2486895

Produktdetails anti-RPS6KA1 Antikörper (FITC)

Target: RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPS6KA1 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Spezifität: Detects ~90 kDa.

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte

Aufreinigung: Peptide Affinity Purified

Immunogen: Human p90 RSK1 C-terminal peptide, conjugated to KLH

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• ICC/IF (1:50)
• optimal dilutions for assays should be determined by the user.

Kommentare:

0.25 mg/ml was sufficient for detection of ABIN2486895 in lysates prepared from mouse brain, spleen and intestine.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 50 % glycerol, 0.01 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu RPS6KA1

Target: RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

Andere Bezeichnung: RSK1 (RPS6KA1 Produkte)

Synonyme: HU-1 antikoerper, MAPKAPK1A antikoerper, RSK antikoerper, RSK1 antikoerper, Rsk1 antikoerper, p90rsk antikoerper, rsk antikoerper, RPS6KA antikoerper, hu-1 antikoerper, mapkapk1a antikoerper, rsk1 antikoerper, wu:fc56h07 antikoerper, zgc:152654 antikoerper, ribosomal protein S6 kinase A1 antikoerper, ribosomal protein S6 kinase polypeptide 1 antikoerper, ribosomal protein S6 kinase A1-like antikoerper, ribosomal protein S6 kinase A1 L homeolog antikoerper, ribosomal protein S6 kinase a, polypeptide 1 antikoerper, RPS6KA1 antikoerper, Rps6ka1 antikoerper, RPS6KA1L antikoerper, rps6ka1.L antikoerper, rps6ka1 antikoerper

Hintergrund: The p90 ribosomal S6 kinase (Rsk) family comprises four mammalian serine/threonine kinases (Rsk1-4). In the past, S6K1 and S6K2 were thought to be the predominant operating S6 kinases, however RSK 1 and 2 have been shown to phosphorylate S6 in response to the ERK pathway, or otherwise known as the extra cellular signal-regulated kinases pathway. RSK 1 in particular is very multifunctional as it participates in nuclear signaling, regulates nuclear factors, regulates several transcription factors like c-Fos, and interacts with the transcriptional coactivator CREB-binding protein. As a result, RSK1 seems to have an important role in cellular growth control and proliferation. (1-5).

Gen-ID: 6195

NCBI Accession: NP_002944

UniProt: Q15418

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades