SLC5A5 Antikörper (AA 468-643) (Biotin)

Produktnummer ABIN2484440

Produktdetails anti-SLC5A5 Antikörper (Biotin)

Target: SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))

Bindungsspezifität: AA 468-643

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SLC5A5 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Antibody Array (AA)

Spezifität: Detects ~97 kDa, non-glycosylated version at 68 kDa. Other minor bands associated with hNIS at 160 kDa, and degradation products at ~30 kDa, and ~15 kDa.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Mannose binding protein hNIS fusion (AA468-643)

Klon: 14F

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• IHC (1:1000)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN2484440 was sufficient for detection of hNIS in 20 μg of transfected COS-7 cell membrane lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu SLC5A5

Target: SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))

Andere Bezeichnung: Sodium Iodide Symporter (SLC5A5 Produkte)

Synonyme: Na(+)/I(-) cotransporter antikoerper, Na(+)/I(-) symporter antikoerper, Nis antikoerper, solute carrier family 5 member 5 antikoerper, Slc5a5 antikoerper

Hintergrund: The sodium iodide symporter (NIS) is an ion pump that actively transports iodide across the basolateral membrane into thyroid epithelial cells (1, 2). This is important step in the process of iodide organificaton and the formation of triiodothyronine and thyroxine (3).

Gen-ID: 6528

NCBI Accession: NP_000444

UniProt: Q92911