SLC38A1 Antikörper (Solute Carrier Family 38 Member 1) (AA 1-63) (Atto 633)

Details for Product anti-SLC38A1 Antibody No. ABIN2482513
Antigen
  • ATA1
  • NAT2
  • SAT1
  • SNAT1
  • AA408026
  • AA409865
  • AL022800
  • AU015942
  • Ata1
  • GlnT
  • Sat1
  • solute carrier family 38 member 1
  • solute carrier family 38, member 1
  • SLC38A1
  • Slc38a1
Epitop
AA 1-63
62
4
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
88
76
67
4
3
3
2
2
1
1
Wirt
Maus
74
24
1
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser SLC38A1 Antikörper ist konjugiert mit Atto 633
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
92
84
50
29
27
20
7
4
4
1
Optionen
Immunogen Fusion protein amino acids 1- 63 of rat SNAT1
Klon S104-32
Isotyp IgG1
Spezifität Detects ~50 kDa.
Reinigung Protein G Purified
Plasmids, Primers & others Plasmide, Primers & weitere SLC38A1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung SLC38A1 (SLC38A1 Antibody Abstract)
Hintergrund The sodium-coupled neutral amino acid transporters (SNAT) of the SLC38 gene family include System A subtypes SNAT1, SNAT2 and SNAT4 and System N subtypes SNAT3 and SNAT5. The SLC38 transporters are essential for the uptake of nutrients, energy production, metabolism, detoxification, and the cycling of neurotransmitters. The SNAT1 protein, also designated ATA1 or NAT2 is encoded by the human gene SLC38A1 which maps to chromosome 12q13.11. SNAT1 is responsible for the transport of glutamine, an intermediate in the synthesis of urea, and may be involved in the generation of glutamate in the retina. SNAT1 protein may be detected in some tissues such as heart, brain and placenta and expression levels are enriched in certain neuronal populations within the CNS. SNAT1 is not present in astrocytes.
Gen-ID 170567
NCBI Accession NP_620187
UniProt Q9JM15
Applikations-hinweise
  • WB (1:1000)
  • optimal dilutions for assays should be determined by the user.
Kommentare

1 μg/ml of SMC-401 was sufficient for detection of SNAT1 in 20 μg of lysates from neocortical neurons cultured under amino acid starvation conditions and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Bilder des Herstellers
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Solute Carrier Family 38 Member 1 (SLC38A1) (AA 1-63) antibody (Atto 633) (ABIN2482513) Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-SNAT1 Monoclonal Ant...
Western Blotting (WB) image for anti-Solute Carrier Family 38 Member 1 (SLC38A1) (AA 1-63) antibody (Atto 633) (ABIN2482513) Western Blot analysis of Rat brain membrane lysate showing detection of SLC38A1 prote...
Allgemeine Veröffentlichungen Hatanaka, Huang, Wang, Sugawara, Prasad, Leibach, Ganapathy: "Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A." in: Biochimica et biophysica acta, Vol. 1467, Issue 1, pp. 1-6, 2000 (PubMed).

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