DNAJB1 Antikörper (C-Term) (HRP)

Produktnummer ABIN2482315

Produktdetails anti-DNAJB1 Antikörper (HRP)

Target: DNAJB1 (DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1))

Bindungsspezifität: C-Term

Reaktivität: Plasmodium falciparum

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAJB1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Detects ~ 62 kDa. Specific to P. Falciparum and does not cross-react to any protein from Human erythrocytes.

Kreuzreaktivität: Plasmodium falciparum

Aufreinigung: Protein A Purified

Immunogen: C-terminal peptide of Pf11_0513 conjugated to KLH

Anwendungsinformationen

Applikationshinweise:

• WB (1:2000)
• ICC/IF (1:50)
• optimal dilutions for assays should be determined by the user.

Kommentare:

0.9 μg/ml of ABIN2482315 was sufficient for detection of Pf11_0513 in 20 μg of P. falciparum lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.8 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu DNAJB1

Target: DNAJB1 (DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1))

Andere Bezeichnung: HSP40 (DNAJB1 Produkte)

Synonyme: HSPF1 antikoerper, Hdj1 antikoerper, Hsp40 antikoerper, RSPH16B antikoerper, Sis1 antikoerper, CG10578 antikoerper, DNAJ-1 antikoerper, DNAJ1 antikoerper, DROJ1 antikoerper, Dmel\\CG10578 antikoerper, DnaJ1 64EF antikoerper, DroJ1 antikoerper, EU3500 antikoerper, HSP40 antikoerper, HSP40/HDJ1 antikoerper, Hsp-40 antikoerper, anon-WO0140519.166 antikoerper, anon-WO0172774.135 antikoerper, dHDJ1 antikoerper, dHDJ1/HSP40 antikoerper, dHdj1 antikoerper, dhdJ1 antikoerper, dhdj-1 antikoerper, dhdj1 antikoerper, dnaJ-1 antikoerper, droj1 antikoerper, hsp40 antikoerper, dnajb4 antikoerper, hdj1 antikoerper, hspf1 antikoerper, sis1 antikoerper, DnaJ-5 antikoerper, MAS5 antikoerper, dnaJ antikoerper, 0610007I11Rik antikoerper, dnajb1 antikoerper, zf-Hsp40 antikoerper, zgc:101068 antikoerper, DnaJ heat shock protein family (Hsp40) member B1 antikoerper, DnaJ-like-1 antikoerper, DnaJ (Hsp40) homolog 5 antikoerper, type I HSP40 co-chaperone YDJ1 antikoerper, DnaJ protein antikoerper, molecular chaperone DnaJ antikoerper, DnaJ (Hsp40) homolog, subfamily B, member 1a antikoerper, DNAJB1 antikoerper, Dnajb1 antikoerper, DnaJ-1 antikoerper, dnajb1 antikoerper, DnaJ-5 antikoerper, YDJ1 antikoerper, dnaJ antikoerper, dnajb1a antikoerper

Hintergrund: DnaJ/HSP40 proteins have been preserved throughout evolution and are important for protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of chaperone proteins, HSP70s. Because the ATP hydrolysis is essential for the activity of HSP70s, DnaJ/HSP40 proteins actually determine the activity of HSP70s by stabilizing their interaction with substrate proteins. DnaJ/HSP40 proteins all contain the J domain through which they bind to HSP70s. HSP40, also known as HDJ1 (1), is a basic mammalian 40 kDa heat shock protein which is not only homologous to the bacterial heat shock protein (DnaJ), but also yeast DnaJ-related proteins such as SCJ1, Sec63/Npl1, YDJ1 and SIS1 (2-6). HSP 40 is inducible by stress including heat after which is moves from the cytoplasm to the nucleus and nucleoli, an intracellular pattern similar to HSC70/HSP70, the mammalian homologues of the bacterial heat shock protein, DnaK (3). PF11_0513 belongs to the HSP40 family of chaperones. This protein has a Plasmodium export element (PEXEL). It is exported out of the parasite into the infected erythrocytic compartment.

Gen-ID: 811046

NCBI Accession: XP_001348169

UniProt: Q8IHM7