TRAP1 Antikörper (AA 1-59) (Atto 390)
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- Target Alle TRAP1 Antikörper anzeigen
- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
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Bindungsspezifität
- AA 1-59
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TRAP1 Antikörper ist konjugiert mit Atto 390
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Detects ~75 kDa, multiple isoforms.
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Protein A Purified
- Immunogen
- Human recombinant TRAP1 (amino acids 1-59 removed - transit peptide)
- Top Product
- Discover our top product TRAP1 Primärantikörper
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- Applikationshinweise
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- WB (1:1000)
- ICC/IF (1:120)
- optimal dilutions for assays should be determined by the user.
- Kommentare
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1 μg/ml of ABIN2482010 was sufficient for detection of Trap-1 in 20 μg of Hela Cell lysate by ECL immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- Target
- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
- Andere Bezeichnung
- TRAP1 (TRAP1 Produkte)
- Synonyme
- HSP 75 antikoerper, HSP75 antikoerper, HSP90L antikoerper, TRAP-1 antikoerper, 2410002K23Rik antikoerper, fc85a11 antikoerper, wu:fc85a11 antikoerper, TNF receptor associated protein 1 antikoerper, TNF receptor-associated protein 1 antikoerper, TRAP1 antikoerper, Trap1 antikoerper, trap1 antikoerper
- Hintergrund
- The 90 kDa heat shock protein (HSP90) family of molecular chaperones is a highly conserved family of proteins that play an important physiological role. HSP90 is involved in numerous cellular processes but is best known for its association with signal transduction machinery. A recently cloned homolog of HSP90 is the tumor necrosis factor receptor-associated protein (TRAP1). Like HSP90, TRAP1 is found to beassociated with numerous proteins involved in diverse actions (1, 2). Immunofluorescence data has shown TRAP1 to be localized in the mitochondria of mammalian cells. This observation and the fact that TRAP1 is shown to have a mitochondrial targeting presequence strongly implicates TRAP1 as a mitochondrial matrix protein (3).
- Gen-ID
- 10131
- NCBI Accession
- NP_057376
- UniProt
- Q12931
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