SPRY4 Antikörper (AA 306-322)

Produktnummer ABIN2470367

Produktdetails anti-SPRY4 Antikörper

Target: SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))

Bindungsspezifität: AA 306-322

Reaktivität: Human, Schimpanse

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPRY4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Immunoaffinity Chromatography

Immunogen: SPRY4 antibody was raised against amino acids 306-322 of SPRY4 (Human).

Anwendungsinformationen

Applikationshinweise: SPRY4 antibody can be used in Western Blot, immunohistochemistry starting at 1:200, and immunoprecipitation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store SPRY4 antibody at 4 °C or -20 °C.

Details zu SPRY4

Target: SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))

Andere Bezeichnung: SPRY4 (SPRY4 Produkte)

Synonyme: SPRY4 antikoerper, LOC100218545 antikoerper, HH17 antikoerper, A030006O18Rik antikoerper, sprouty4 antikoerper, sprouty RTK signaling antagonist 4 antikoerper, sprouty (Drosophila) homolog 4 antikoerper, sprouty homolog 4 (Drosophila) antikoerper, Spry4 antikoerper, SPRY4 antikoerper, spry4 antikoerper

Hintergrund: Sprouty-4 (also known as SPRY4) is an inhibitor of the insulin receptor and EGFR-transduced mitogen-activated protein kinase (MAPK) signaling pathway downstream of FGF and EGF receptor tyrosine kinase activation. It is positioned upstream of RAS activation and impairs the formation of active GTP-RAS. SPRY4 is widely expressed, with different isoforms. The protein consists of 322 amino acids, with a cysteine-rich region, Src homology 3 binding regions, proline-rich regions, and a PEST sequence. It is expressed predominantly in the cytoplasm. Northern results show bands across most tissues, with strongest expression in heart, brain, placenta, lung, and intestine.

Gen-ID: 81848

UniProt: Q9C004