RAMP3 antibody can be used in ELISA starting at 1:3000 - 1:6000, Western Blot starting at 1:3000 - 1:6000, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS, 0.01 % sodium azide, 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
As with all antibodies avoid freeze/thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store RAMP3 antibody at 4 °C or -20 °C.
Target
RAMP3
(Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))
RAMP3 antikoerper, ramp3 antikoerper, AI850306 antikoerper, receptor activity modifying protein 3 antikoerper, receptor (G protein-coupled) activity modifying protein 3 antikoerper, Receptor activity-modifying protein 3 antikoerper, receptor (calcitonin) activity modifying protein 3 antikoerper, RAMP3 antikoerper, ramp3 antikoerper, Ramp3 antikoerper
Hintergrund
RAMP3 is a member of the RAMP family of single-transmembrane-domain proteins, called receptor-activity-modifying proteins. RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. Co-expression of RAMP3 with CRLR results in the production of a functional adrenomedullin receptor.