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Hintergrund
PTM: Subjected to an intracellular maturation process yielding a 120 kDa N-terminal fragment containing the metalloproteinase, disintegrin, one TSP type-1 and the Cys-rich domains and a 83 kDa C-terminal fragment containing the spacer 2 and four TSP type-1 domains.
SIMILARITY: Contains 8 TSP type-1 domains.
COFACTOR: Binds 1 zinc ion per subunit (By similarity).