ACTR1B Antikörper

Produktnummer ABIN2463495

Produktdetails anti-ACTR1B Antikörper

Target: ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACTR1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ACTR1B.

Anwendungsinformationen

Applikationshinweise: ACTR1B antibody can be used for detection of ACTR1B by ELISA at 1:62500. ACTR1B antibody can be used for detection of ACTR1B by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ACTR1B antibody at -20 °C.

Details zu ACTR1B

Target: ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))

Andere Bezeichnung: ACTR1B (ACTR1B Produkte)

Synonyme: ARP1B antikoerper, CTRN2 antikoerper, PC3 antikoerper, 2310066K23Rik antikoerper, AA960180 antikoerper, AI851923 antikoerper, Arp1b antikoerper, ACTR1B antikoerper, ARP1 actin related protein 1 homolog B antikoerper, ARP1 actin-related protein 1B, centractin beta antikoerper, ARP1 actin-related protein 1 homolog B antikoerper, ARP1 actin-related protein 1 homolog B, centractin beta (yeast) antikoerper, beta-centractin antikoerper, ACTR1B antikoerper, Actr1b antikoerper, LOC100594459 antikoerper

Hintergrund: ACTR1B is a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. ACTR1B, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90 % amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins are of equal length and share 90 % amino acid identity. They are present in a constant ratio of approximately 1:15 in the dynactin complex.

Molekulargewicht: 42 kDa

Gen-ID: 10120

NCBI Accession: NP_005726

UniProt: P42025