COPA Antikörper

Produktnummer ABIN2463478

Produktdetails anti-COPA Antikörper

Target: COPA (Coatomer Protein Complex, Subunit alpha (COPA))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COPA.

Anwendungsinformationen

Applikationshinweise: COPA antibody can be used for detection of COPA by ELISA at 1:62500. COPA antibody can be used for detection of COPA by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store COPA antibody at -20 °C.

Details zu COPA

Target: COPA (Coatomer Protein Complex, Subunit alpha (COPA))

Andere Bezeichnung: COPA (COPA Produkte)

Synonyme: COPA antikoerper, DDBDRAFT_0189693 antikoerper, DDBDRAFT_0233797 antikoerper, DDB_0189693 antikoerper, DDB_0233797 antikoerper, DKFZp469O221 antikoerper, AU040324 antikoerper, xenin antikoerper, HEP-COP antikoerper, cb281 antikoerper, fb13c12 antikoerper, wu:fb13c12 antikoerper, coatomer protein complex subunit alpha antikoerper, WD40 repeat-containing protein antikoerper, Coatomer subunit alpha antikoerper, coatomer protein complex, subunit alpha antikoerper, coatomer protein complex subunit alpha L homeolog antikoerper, COPA antikoerper, copA antikoerper, cgd8_860 antikoerper, Chro.80105 antikoerper, AFUA_3G08840 antikoerper, copa antikoerper, Copa antikoerper, copa.L antikoerper

Hintergrund: In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone.In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.

Molekulargewicht: 135 kDa

Gen-ID: 1314

NCBI Accession: NP_004362

UniProt: P53621

Pathways: Hormone Activity