ZP4 Antikörper

Produktnummer ABIN2463282

Produktdetails anti-ZP4 Antikörper

Target: ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZP4.

Anwendungsinformationen

Applikationshinweise: ZP4 antibody can be used for detection of ZP4 by ELISA at 1:1562500. ZP4 antibody can be used for detection of ZP4 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ZP4 antibody at -20 °C.

Details zu ZP4

Target: ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))

Andere Bezeichnung: ZP4 (ZP4 Produkte)

Synonyme: ZPB antikoerper, xlZPB antikoerper, lzpb-a antikoerper, MGC154827 antikoerper, zbp antikoerper, zp1 antikoerper, ZBP antikoerper, TAC4 antikoerper, MGC154888 antikoerper, ZP1 antikoerper, Zp-4 antikoerper, ZP3-ALPHA antikoerper, ZP antikoerper, Zp-X antikoerper, zona pellucida glycoprotein 4 S homeolog antikoerper, zona pellucida glycoprotein 4 antikoerper, zona pellucida glycoprotein 4 L homeolog antikoerper, zp4.S antikoerper, zp4 antikoerper, ZP4 antikoerper, zp4.L antikoerper, Zp4 antikoerper

Hintergrund: The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix.The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 49 kDa

Gen-ID: 57829

NCBI Accession: NP_067009

UniProt: Q12836