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PCMT1 Antikörper

PCMT1 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2463200
  • Target Alle PCMT1 Antikörper anzeigen
    PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
    Reaktivität
    • 49
    • 21
    • 20
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 44
    • 5
    Kaninchen
    Klonalität
    • 44
    • 5
    Polyklonal
    Konjugat
    • 26
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PCMT1 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 13
    • 13
    • 12
    • 10
    • 10
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    Antibody is purified by protein A chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCMT1.
    Top Product
    Discover our top product PCMT1 Primärantikörper
  • Applikationshinweise
    PCMT1 antibody can be used for detection of PCMT1 by ELISA at 1:312500. PCMT1 antibody can be used for detection of PCMT1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Konzentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handhabung
    As with any antibody avoid repeat freeze-thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCMT1 antibody at -20 °C.
  • Target
    PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
    Andere Bezeichnung
    PCMT1 (PCMT1 Produkte)
    Synonyme
    PIMT antikoerper, C79501 antikoerper, PCM antikoerper, PCMT antikoerper, etID309741.20 antikoerper, fj13d06 antikoerper, pimt antikoerper, wu:fj13d06 antikoerper, protein-L-isoaspartate (D-aspartate) O-methyltransferase antikoerper, protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 antikoerper, protein-L-isoaspartate (D-aspartate) O-methyltransferase L homeolog antikoerper, protein-L-isoaspartate(D-aspartate)O-methyltransferase antikoerper, PCMT1 antikoerper, Pcmt1 antikoerper, pcmt1.L antikoerper, pcmt1 antikoerper, pcmt antikoerper
    Hintergrund
    Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Molekulargewicht
    25 kDa
    Gen-ID
    5110
    NCBI Accession
    NP_005380
    UniProt
    P22061
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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