DTX2 Antikörper
-
- Target Alle DTX2 Antikörper anzeigen
- DTX2 (Deltex Homolog 2 (DTX2))
-
Reaktivität
- Human, Hund, Zebrafisch (Danio rerio)
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser DTX2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DTX2.
- Top Product
- Discover our top product DTX2 Primärantikörper
-
-
- Applikationshinweise
- DTX2 antibody can be used for detection of DTX2 by ELISA at 1:312500. DTX2 antibody can be used for detection of DTX2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store DTX2 antibody at -20 °C.
-
- Target
- DTX2 (Deltex Homolog 2 (DTX2))
- Andere Bezeichnung
- DTX2 (DTX2 Produkte)
- Synonyme
- RNF58 antikoerper, 2610524D08Rik antikoerper, AA408415 antikoerper, AU022494 antikoerper, Deltex2 antikoerper, dtx2 antikoerper, deltex E3 ubiquitin ligase 2 antikoerper, probable E3 ubiquitin-protein ligase DTX2 antikoerper, deltex 2, E3 ubiquitin ligase antikoerper, deltex 2, E3 ubiquitin ligase S homeolog antikoerper, DTX2 antikoerper, Dtx2 antikoerper, LOC735784 antikoerper, LOC747633 antikoerper, dtx2 antikoerper, dtx2.S antikoerper
- Hintergrund
- DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
- Molekulargewicht
- 62 kDa, 67 kDa, 67 kDa, 67 kDa, 93 kDa, 26 kDa, 93 kDa, 45 kDa
- Gen-ID
- 113878
- NCBI Accession
- NP_001096066
- UniProt
- Q6XM87
- Pathways
- Notch Signalweg
-