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NXF1 Antikörper

NXF1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2462207
  • Target Alle NXF1 Antikörper anzeigen
    NXF1 (Nuclear RNA Export Factor 1 (NXF1))
    Reaktivität
    • 56
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    Human
    Wirt
    • 56
    • 1
    Kaninchen
    Klonalität
    • 47
    • 10
    Polyklonal
    Konjugat
    • 30
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser NXF1 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 22
    • 19
    • 9
    • 8
    • 6
    • 4
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    Antibody is purified by protein A chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NXF1.
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    Discover our top product NXF1 Primärantikörper
  • Applikationshinweise
    NXF1 antibody can be used for detection of NXF1 by ELISA at 1:312500. NXF1 antibody can be used for detection of NXF1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Konzentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handhabung
    As with any antibody avoid repeat freeze-thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store NXF1 antibody at -20 °C.
  • Target
    NXF1 (Nuclear RNA Export Factor 1 (NXF1))
    Andere Bezeichnung
    NXF1 (NXF1 Produkte)
    Synonyme
    im:7156527 antikoerper, wu:fc12d06 antikoerper, MGC82224 antikoerper, NXF1 antikoerper, tap antikoerper, mex67 antikoerper, MEX67 antikoerper, TAP antikoerper, Mex67 antikoerper, Mvb1 antikoerper, Tap antikoerper, Mex67h antikoerper, nuclear RNA export factor 1 antikoerper, nuclear RNA export factor 1 S homeolog antikoerper, Nuclear RNA export factor 1 antikoerper, nxf1 antikoerper, nxf1.S antikoerper, NXF1 antikoerper, LOC100113601 antikoerper, Tsp_03999 antikoerper, Nxf1 antikoerper, nxf-1 antikoerper
    Hintergrund
    NXF1 is one member of a family of nuclear RNA export factor. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF1 shuttles between the nucleus and the cytoplasm and binds in vivo to poly (A)+ RNA. NXF1 overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly (A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.
    Molekulargewicht
    68 kDa, 40 kDa
    Gen-ID
    10482
    NCBI Accession
    NP_006353
    UniProt
    Q9UBU9
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