SFPQ Antikörper
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- Target Alle SFPQ Antikörper anzeigen
- SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SFPQ Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Aufreinigung
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SFPQ.
- Top Product
- Discover our top product SFPQ Primärantikörper
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- Applikationshinweise
- SFPQ antibody can be used for detection of SFPQ by ELISA at 1:12500. SFPQ antibody can be used for detection of SFPQ by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SFPQ antibody at -20 °C.
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- Target
- SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
- Andere Bezeichnung
- SFPQ (SFPQ Produkte)
- Synonyme
- 1110004P21Rik antikoerper, 2810416M14Rik antikoerper, 5730453G22Rik antikoerper, 9030402K04Rik antikoerper, AU021830 antikoerper, D4Ertd314e antikoerper, Gm12940 antikoerper, OTTMUSG00000009329 antikoerper, PSF antikoerper, REP1 antikoerper, hm:zeh0027 antikoerper, wu:fa11h12 antikoerper, wu:fd10f03 antikoerper, zgc:85935 antikoerper, POMP100 antikoerper, splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) antikoerper, splicing factor proline/glutamine-rich antikoerper, splicing factor proline and glutamine rich antikoerper, Sfpq antikoerper, sfpq antikoerper, SFPQ antikoerper
- Hintergrund
- SFPQ is DNA- and RNA binding protein. It is essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as an heteromer with NONO. It binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. It interacts with U5 snRNA. It may be involved in a pre-mRNA coupled splicing and polyadenylation process as component of a snRNP-free complex with SNRPA/U1A. SFPQ may be involved in homologous DNA pairing. SFPQ is involved in transcriptional regulation. It binds the DNA sequence 5'-CTGAGTC-3' in the insulin-like growth factor response element (IGFRE) and inhibits IGF-I-stimulated transcriptional activity.
- Molekulargewicht
- 78 kDa
- Gen-ID
- 6421
- NCBI Accession
- NP_005057
- UniProt
- P23246
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