GSC2 Antikörper

Produktnummer ABIN2461751

Produktdetails anti-GSC2 Antikörper

Target: GSC2 (Goosecoid Homeobox 2 (GSC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GSCL.

Anwendungsinformationen

Applikationshinweise: GSCL antibody can be used for detection of GSCL by ELISA at 1:1562500. GSCL antibody can be used for detection of GSCL by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GSCL antibody at -20 °C.

Details zu GSC2

Target: GSC2 (Goosecoid Homeobox 2 (GSC2))

Andere Bezeichnung: GSCL (GSC2 Produkte)

Synonyme: Gscl antikoerper, GSCL antikoerper, 4930568H22Rik antikoerper, GSC-2 antikoerper, goosecoid homeobox 2 antikoerper, goosecoid homebox 2 antikoerper, Gsc2 antikoerper, GSC2 antikoerper

Hintergrund: Goosecoidlike (GSCL) resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology.Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development.

Molekulargewicht: 22 kDa

Gen-ID: 2928

NCBI Accession: NP_005306

UniProt: O15499