SAP30 Antikörper

Produktnummer ABIN2461707

Produktdetails anti-SAP30 Antikörper

Target: SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAP30 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SAP30.

Anwendungsinformationen

Applikationshinweise: SAP30 antibody can be used for detection of SAP30 by ELISA at 1:312500. SAP30 antibody can be used for detection of SAP30 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SAP30 antibody at -20 °C.

Details zu SAP30

Target: SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))

Andere Bezeichnung: SAP30 (SAP30 Produkte)

Synonyme: 30kDa antikoerper, Sin3A associated protein 30 antikoerper, sin3 associated polypeptide antikoerper, Sin3A associated protein 30kDa S homeolog antikoerper, SAP30 antikoerper, Sap30 antikoerper, sap30.S antikoerper

Hintergrund: Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP30 is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3.

Molekulargewicht: 23 kDa

Gen-ID: 8819

NCBI Accession: NP_003855

UniProt: O75446