KCNN1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
KCNN1 antibody can be used for detection of KCNN1 by ELISA at 1:312500. KCNN1 antibody can be used for detection of KCNN1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Konzentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handhabung
As with any antibody avoid repeat freeze-thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
For short periods of storage (days) store at 4 °C. For longer periods of storage, store KCNN1 antibody at -20 °C.
Target
KCNN1
(Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 1 (KCNN1))
KCNN1 antikoerper, kcnn1 antikoerper, si:ch211-200a16.1 antikoerper, sk1 antikoerper, hsk1 antikoerper, skca1 antikoerper, MGC145919 antikoerper, KCa2.1 antikoerper, SK1 antikoerper, SKCA1 antikoerper, hSK1 antikoerper, AI854248 antikoerper, potassium calcium-activated channel subfamily N member 1 antikoerper, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b antikoerper, potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 antikoerper, small conductance calcium-activated potassium channel protein 1 antikoerper, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 antikoerper, KCNN1 antikoerper, kcnn1b antikoerper, kcnn1 antikoerper, LOC100456154 antikoerper, Kcnn1 antikoerper
Hintergrund
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. KCNN1 is a member of the KCNN family of potassium channels.