LMX1A Antikörper
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- Target Alle LMX1A Antikörper anzeigen
- LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LMX1A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LMX1A.
- Top Product
- Discover our top product LMX1A Primärantikörper
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- Applikationshinweise
- LMX1A antibody can be used for detection of LMX1A by ELISA at 1:62500. LMX1A antibody can be used for detection of LMX1A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store LMX1A antibody at -20 °C.
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- Target
- LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))
- Andere Bezeichnung
- LMX1A (LMX1A Produkte)
- Synonyme
- Lmx1.1 antikoerper, dr antikoerper, dreher antikoerper, sst antikoerper, LMX1 antikoerper, LMX1.1 antikoerper, si:ch211-260g14.3 antikoerper, LIM homeobox transcription factor 1 alpha antikoerper, LIM homeobox transcription factor 1, alpha antikoerper, Lmx1a antikoerper, LMX1A antikoerper, lmx1a antikoerper
- Hintergrund
- Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS, MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin. Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS, MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin (German et al., 1994 [PubMed 7698771]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-199 AL160058.8 14249-14447 c 200-2447 AK127724.1 362-2609 2448-3382 AL390730.12 9415-10349 c
- Molekulargewicht
- 43 kDa
- Gen-ID
- 4009
- NCBI Accession
- NP_796372
- UniProt
- Q8TE12
- Pathways
- Dopaminergic Neurogenesis
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