NFX1 Antikörper

Produktnummer ABIN2460119

Produktdetails anti-NFX1 Antikörper

Target: NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFX1.

Anwendungsinformationen

Applikationshinweise: NFX1 antibody can be used for detection of NFX1 by ELISA at 1:312500. NFX1 antibody can be used for detection of NFX1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NFX1 antibody at -20 °C.

Details zu NFX1

Target: NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))

Andere Bezeichnung: NFX1 (NFX1 Produkte)

Synonyme: NFX1 antikoerper, NFX2 antikoerper, 1300017N15Rik antikoerper, 3000003M19Rik antikoerper, NFX.1 antikoerper, TEG-42 antikoerper, Tex42 antikoerper, nuclear transcription factor, X-box binding 1 antikoerper, nuclear transcription factor, x-box binding 1 antikoerper, NFX1 antikoerper, CpipJ_CPIJ011986 antikoerper, nfx1 antikoerper, Nfx1 antikoerper

Hintergrund: MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.

Molekulargewicht: 124 kDa

Gen-ID: 4799

NCBI Accession: NP_002495

UniProt: Q12986