FN3KRP Antikörper

Produktnummer ABIN2460081

Produktdetails anti-FN3KRP Antikörper

Target: FN3KRP (Fructosamine 3 Kinase Related Protein (FN3KRP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FN3KRP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FN3KRP.

Anwendungsinformationen

Applikationshinweise: FN3KRP antibody can be used for detection of FN3KRP by ELISA at 1:1562500. FN3KRP antibody can be used for detection of FN3KRP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FN3KRP antibody at -20 °C.

Details zu FN3KRP

Target: FN3KRP (Fructosamine 3 Kinase Related Protein (FN3KRP))

Andere Bezeichnung: FN3KRP (FN3KRP Produkte)

Synonyme: FN3KL antikoerper, FN3K-RP antikoerper, fn3k antikoerper, fn3kl antikoerper, MGC145992 antikoerper, DKFZP469K211 antikoerper, RGD1304570 antikoerper, zgc:101634 antikoerper, fructosamine 3 kinase related protein antikoerper, fructosamine-3-kinase-related protein antikoerper, FN3KRP antikoerper, Fn3krp antikoerper, fn3krp antikoerper

Hintergrund: FN3KRP phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein-bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation.FN3KRP and FN3K (MIM 608425) protect proteins from nonenzymatic glycation by phosphorylating the modified amino acid. This phosphorylation destabilizes the sugar-amine linkage and leads to spontaneous decomposition (Conner et al., 2004 [PubMed 15381090]).

Molekulargewicht: 34 kDa

Gen-ID: 79672

NCBI Accession: NP_078895

UniProt: Q9HA64