LRRC8A Antikörper

Produktnummer ABIN2459288

Produktdetails anti-LRRC8A Antikörper

Target: LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRC8A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LRRC8A.

Anwendungsinformationen

Applikationshinweise: LRRC8A antibody can be used for detection of LRRC8A by ELISA at 1:62500. LRRC8A antibody can be used for detection of LRRC8A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store LRRC8A antibody at -20 °C.

Details zu LRRC8A

Target: LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

Andere Bezeichnung: LRRC8A (LRRC8A Produkte)

Synonyme: AGM5 antikoerper, LRRC8 antikoerper, Lrrc8 antikoerper, mKIAA1437 antikoerper, wu:fb18g12 antikoerper, wu:fi21b10 antikoerper, LLRC8A antikoerper, leucine rich repeat containing 8 VRAC subunit A antikoerper, leucine rich repeat containing 8A antikoerper, leucine rich repeat containing 8 VRAC subunit Aa antikoerper, leucine-rich repeat containing 8 family member A S homeolog antikoerper, leucine rich repeat containing 8 family member A antikoerper, LRRC8A antikoerper, Lrrc8a antikoerper, lrrc8aa antikoerper, lrrc8a.S antikoerper

Hintergrund: LRRC8A is a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. LRRC8A is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Molekulargewicht: 94 kDa

Gen-ID: 56262

NCBI Accession: NP_062540

UniProt: Q8IWT6