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PCDHA5 Antikörper

PCDHA5 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2459279
  • Target Alle PCDHA5 Antikörper anzeigen
    PCDHA5 (Protocadherin alpha 5 (PCDHA5))
    Reaktivität
    • 19
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 18
    • 1
    Kaninchen
    Klonalität
    • 18
    • 1
    Polyklonal
    Konjugat
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PCDHA5 Antikörper ist unkonjugiert
    Applikation
    • 19
    • 15
    • 14
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDHA5.
    Top Product
    Discover our top product PCDHA5 Primärantikörper
  • Applikationshinweise
    PCDHA5 antibody can be used for detection of PCDHA5 by ELISA at 1:312500. PCDHA5 antibody can be used for detection of PCDHA5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Konzentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handhabung
    As with any antibody avoid repeat freeze-thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCDHA5 antibody at -20 °C.
  • Target
    PCDHA5 (Protocadherin alpha 5 (PCDHA5))
    Andere Bezeichnung
    PCDHA5 (PCDHA5 Produkte)
    Synonyme
    CNR6 antikoerper, CNRN6 antikoerper, CNRS6 antikoerper, CRNR6 antikoerper, PCDH-ALPHA5 antikoerper, Cnr6 antikoerper, Crnr6 antikoerper, rCNRv05 antikoerper, PCDHA5 antikoerper, Pcdha5 antikoerper, protocadherin alpha 5 antikoerper, protocadherin alpha-5 antikoerper, PCDHA5 antikoerper, Pcdha5 antikoerper, LOC100738784 antikoerper, LOC100847156 antikoerper, LOC100713870 antikoerper, LOC100629824 antikoerper
    Hintergrund
    The gene encoding PCDHA5 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. PCDHA5 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA5 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
    Molekulargewicht
    99 kDa
    Gen-ID
    56143
    NCBI Accession
    NP_061731
    UniProt
    Q9Y5H7
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