PSMC3IP Antikörper

Produktnummer ABIN2459129

Produktdetails anti-PSMC3IP Antikörper

Target: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMC3IP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMC3IP.

Anwendungsinformationen

Applikationshinweise: PSMC3IP antibody can be used for detection of PSMC3IP by ELISA at 1:1562500. PSMC3IP antibody can be used for detection of PSMC3IP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PSMC3IP antibody at -20 °C.

Details zu PSMC3IP

Target: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Andere Bezeichnung: PSMC3IP (PSMC3IP Produkte)

Synonyme: PSMC3IP antikoerper, Arabidopsis Hop2 homolog antikoerper, T6J4.9 antikoerper, T6J4_9 antikoerper, C79099 antikoerper, GT198 antikoerper, HOP2 antikoerper, Tbpip antikoerper, HUMGT198A antikoerper, ODG3 antikoerper, TBPIP antikoerper, Gt198 antikoerper, zgc:86785 antikoerper, PSMC3 interacting protein antikoerper, homologous-pairing protein 2 homolog antikoerper, Homologous-pairing protein 2 homolog antikoerper, homologous-pairing protein 2 homolog-like antikoerper, Tat-binding protein 1(Tbp-1)-interacting protein (TBPIP) antikoerper, proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein antikoerper, PSMC3 interacting protein L homeolog antikoerper, PSMC3IP antikoerper, LOC726449 antikoerper, LOC100165513 antikoerper, hop2 antikoerper, psmc3ip antikoerper, LOC100633854 antikoerper, LOC100650062 antikoerper, LOC789362 antikoerper, AHP2 antikoerper, Psmc3ip antikoerper, psmc3ip.L antikoerper

Hintergrund: PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.

Molekulargewicht: 24 kDa

Gen-ID: 29893

NCBI Accession: NP_037422