KIRREL Antikörper

Produktnummer ABIN2459109

Produktdetails anti-KIRREL Antikörper

Target: KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIRREL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KIRREL.

Anwendungsinformationen

Applikationshinweise: KIRREL antibody can be used for detection of KIRREL by ELISA at 1:312500. KIRREL antibody can be used for detection of KIRREL by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KIRREL antibody at -20 °C.

Details zu KIRREL

Target: KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))

Andere Bezeichnung: KIRREL (NEPH1 Produkte)

Synonyme: NEPH1 antikoerper, 6720469N11Rik antikoerper, Kirrel1 antikoerper, Neph1 antikoerper, nephrin related antikoerper, kirre like nephrin family adhesion molecule 1 antikoerper, kin of IRRE like (Drosophila) antikoerper, Smp_104390 antikoerper, Smp_140170 antikoerper, KIRREL1 antikoerper, Kirrel antikoerper, Kirrel1 antikoerper

Hintergrund: KIRREL (NEPH1) is a member of the nephrin-like protein family, which includes NEPH2 and NEPH3. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2, MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).

Molekulargewicht: 66 kDa

Gen-ID: 55243

NCBI Accession: NP_060710

UniProt: Q5W0F9

Pathways: Regulation of Actin Filament Polymerization