WNT6 antibody can be used for detection of WNT6 by ELISA at 1:312500. WNT6 antibody can be used for detection of WNT6 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Konzentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handhabung
As with any antibody avoid repeat freeze-thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
For short periods of storage (days) store at 4 °C. For longer periods of storage, store WNT6 antibody at -20 °C.
Target
WNT6
(Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))
WNT6 antikoerper, si:dkey-31m21.2 antikoerper, Wnt6 antikoerper, AA409270 antikoerper, Wnt-6 antikoerper, Xwnt-6 antikoerper, wnt-6 antikoerper, wnt6-A antikoerper, xWnt6 antikoerper, Wnt family member 6 antikoerper, wingless-type MMTV integration site family, member 6b antikoerper, wingless-type MMTV integration site family, member 6 antikoerper, Wnt family member 6 S homeolog antikoerper, WNT6 antikoerper, Wnt6 antikoerper, wnt6b antikoerper, wnt6.S antikoerper
Hintergrund
The WNT family consists of several secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT6 is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The WNT6 protein overexpression may play key roles in carcinogenesis. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97 % identical to the mouse Wnt6 protein at the amino acid level.