MMP20 Antikörper

Produktnummer ABIN2459028

Produktdetails anti-MMP20 Antikörper

Target: MMP20 (Matrix Metalloproteinase 20 (MMP20))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP20 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MMP20.

Anwendungsinformationen

Applikationshinweise: MMP20 antibody can be used for detection of MMP20 by ELISA at 1:312500. MMP20 antibody can be used for detection of MMP20 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MMP20 antibody at -20 °C.

Details zu MMP20

Target: MMP20 (Matrix Metalloproteinase 20 (MMP20))

Andere Bezeichnung: MMP20 (MMP20 Produkte)

Synonyme: AI2A2 antikoerper, MMP-20 antikoerper, MMP25 antikoerper, MMP20 antikoerper, mmp20 antikoerper, matrix metallopeptidase 20 antikoerper, matrix metallopeptidase 20 L homeolog antikoerper, matrix metallopeptidase 20 (enamelysin) antikoerper, MMP20 antikoerper, mmp20.L antikoerper, Mmp20 antikoerper

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP20 degrades amelogenin, the major protein component of dental enamel matrix, and so the protein is thought to play a role in tooth enamel formation. A mutation in the gene encoding MMP20, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and so the protein is thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes that localizes to chromosome 11q22.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 43 kDa

Gen-ID: 9313

NCBI Accession: NP_004762

UniProt: O60882