HERC5 Antikörper

Produktnummer ABIN2458718

Produktdetails anti-HERC5 Antikörper

Target: HERC5 (Hect Domain and RLD 5 (HERC5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HERC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HERC5.

Anwendungsinformationen

Applikationshinweise: HERC5 antibody can be used for detection of HERC5 by ELISA at 1:312500. HERC5 antibody can be used for detection of HERC5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HERC5 antibody at -20 °C.

Details zu HERC5

Target: HERC5 (Hect Domain and RLD 5 (HERC5))

Andere Bezeichnung: HERC5 (HERC5 Produkte)

Synonyme: HERC5 antikoerper, CEB1 antikoerper, CEBP1 antikoerper, HECT and RLD domain containing E3 ubiquitin protein ligase 5 antikoerper, hect domain and RLD 5 antikoerper, HERC5 antikoerper

Hintergrund: HERC5 is a member of the HERC family of ubiquitin ligases.It contains a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulates expression of HERC5 protein in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets.This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.

Molekulargewicht: 117 kDa

Gen-ID: 51191

NCBI Accession: NP_057407

UniProt: Q69G20