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RNF139 Antikörper

RNF139 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2458704
  • Target Alle RNF139 Antikörper anzeigen
    RNF139 (Ring Finger Protein 139 (RNF139))
    Reaktivität
    • 18
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 29
    • 3
    • 1
    Kaninchen
    Klonalität
    • 31
    • 2
    Polyklonal
    Konjugat
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RNF139 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 13
    • 13
    • 10
    • 6
    • 5
    • 3
    Western Blotting (WB), ELISA
    Aufreinigung
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF139.
    Top Product
    Discover our top product RNF139 Primärantikörper
  • Applikationshinweise
    RNF139 antibody can be used for detection of RNF139 by ELISA at 1:312500. RNF139 antibody can be used for detection of RNF139 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Konzentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handhabung
    As with any antibody avoid repeat freeze-thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store RNF139 antibody at -20 °C.
  • Target
    RNF139 (Ring Finger Protein 139 (RNF139))
    Andere Bezeichnung
    RNF139 (RNF139 Produkte)
    Synonyme
    HRCA1 antikoerper, RCA1 antikoerper, TRC8 antikoerper, 4930555P18Rik antikoerper, zgc:175173 antikoerper, rnf139 antikoerper, ring finger protein 139 antikoerper, ring finger protein 139 S homeolog antikoerper, RNF139 antikoerper, Rnf139 antikoerper, rnf139 antikoerper, rnf139.S antikoerper
    Hintergrund
    RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t (3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t (3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
    Molekulargewicht
    76 kDa
    Gen-ID
    11236
    NCBI Accession
    NP_009149
    UniProt
    Q8WU17
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