UBE2D3 Antikörper

Produktnummer ABIN2458700

Produktdetails anti-UBE2D3 Antikörper

Target: UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2D3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UBE2D3.

Anwendungsinformationen

Applikationshinweise: UBE2D3 antibody can be used for detection of UBE2D3 by ELISA at 1:1562500. UBE2D3 antibody can be used for detection of UBE2D3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store UBE2D3 antibody at -20 °C.

Details zu UBE2D3

Target: UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))

Andere Bezeichnung: UBE2D3 (UBE2D3 Produkte)

Synonyme: E2(17)KB3 antikoerper, UBC4/5 antikoerper, UBCH5C antikoerper, eff antikoerper, fb36f02 antikoerper, wu:fb36f02 antikoerper, zgc:56340 antikoerper, 1100001F19Rik antikoerper, 9430029A22Rik antikoerper, AA414951 antikoerper, UBE2D3P antikoerper, Xubc4 antikoerper, e2(17)kb3 antikoerper, ubc4/5 antikoerper, ubch5c antikoerper, ube2d3.1 antikoerper, ube2d2 antikoerper, xubc4 antikoerper, wu:fj13d01 antikoerper, zgc:73200 antikoerper, ubiquitin conjugating enzyme E2 D3 antikoerper, ubiquitin-conjugating enzyme E2D 3 antikoerper, ubiquitin conjugating enzyme E2 D3 L homeolog antikoerper, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), like antikoerper, UBE2D3 antikoerper, ube2d3 antikoerper, Ube2d3 antikoerper, LOC100223566 antikoerper, ube2d3.L antikoerper, ube2d2l antikoerper

Hintergrund: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

Molekulargewicht: 17 kDa

Gen-ID: 7323

NCBI Accession: NP_003331

UniProt: P61077

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades