PDZK1 Antikörper

Produktnummer ABIN2458589

Produktdetails anti-PDZK1 Antikörper

Target: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDZK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PDZK1.

Anwendungsinformationen

Applikationshinweise: PDZK1 antibody can be used for detection of PDZK1 by ELISA at 1:1562500. PDZK1 antibody can be used for detection of PDZK1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PDZK1 antibody at -20 °C.

Details zu PDZK1

Target: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Andere Bezeichnung: PDZK1 (PDZK1 Produkte)

Synonyme: xpdzk1 antikoerper, PDZK1 antikoerper, CAP70 antikoerper, CLAMP antikoerper, NHERF-3 antikoerper, NHERF3 antikoerper, PDZD1 antikoerper, 1700023D20Rik antikoerper, 2610507N21Rik antikoerper, 4921513F16Rik antikoerper, AI267131 antikoerper, AI314638 antikoerper, AL022680 antikoerper, D3Ertd537e antikoerper, Pdzd1 antikoerper, mPDZK1 antikoerper, Clamp antikoerper, PDZ domain containing 1 antikoerper, PDZ domain containing 1 L homeolog antikoerper, PDZK1 antikoerper, pdzk1.L antikoerper, pdzk1 antikoerper, Pdzk1 antikoerper

Hintergrund: PDZK1 is a scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. It may be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, it may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. PDZK1 may play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. PDZK1 may potentiate the CFTR chloride channel activity. It may function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. PDZK1 may be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.

Molekulargewicht: 41 kDa

Gen-ID: 5174

NCBI Accession: XP_001126710

UniProt: Q5T2W1