NXF3 Antikörper

Produktnummer ABIN2458541

Produktdetails anti-NXF3 Antikörper

Target: NXF3 (Nuclear RNA Export Factor 3 (NXF3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NXF3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NXF3.

Anwendungsinformationen

Applikationshinweise: NXF3 antibody can be used for detection of NXF3 by ELISA at 1:312500. NXF3 antibody can be used for detection of NXF3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NXF3 antibody at -20 °C.

Details zu NXF3

Target: NXF3 (Nuclear RNA Export Factor 3 (NXF3))

Andere Bezeichnung: NXF3 (NXF3 Produkte)

Synonyme: NXF3 antikoerper, Gm384 antikoerper, RGD1564923 antikoerper, nuclear RNA export factor 3 antikoerper, NXF3 antikoerper, LOC523530 antikoerper, LOC100060140 antikoerper, LOC100060240 antikoerper, LOC785244 antikoerper, Nxf3 antikoerper

Hintergrund: NXF3 is one member of a family of nuclear RNA export factors. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF3 has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.

Molekulargewicht: 60 kDa

Gen-ID: 56000

NCBI Accession: NP_071335

UniProt: Q9H4D5