RFXAP Antikörper

Produktnummer ABIN2458011

Produktdetails anti-RFXAP Antikörper

Target: RFXAP (Regulatory Factor X-Associated Protein (RFXAP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RFXAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RFXAP.

Anwendungsinformationen

Applikationshinweise: RFXAP antibody can be used for detection of RFXAP by ELISA at 1:62500. RFXAP antibody can be used for detection of RFXAP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RFXAP antibody at -20 °C.

Details zu RFXAP

Target: RFXAP (Regulatory Factor X-Associated Protein (RFXAP))

Andere Bezeichnung: RFXAP (RFXAP Produkte)

Synonyme: RFXAP antikoerper, 5730495K23Rik antikoerper, regulatory factor X associated protein antikoerper, regulatory factor X-associated protein antikoerper, RFXAP antikoerper, rfxap antikoerper, Rfxap antikoerper

Hintergrund: RFXAP is part of the RFX complex that binds to the X-box of MHC II promoters.Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 28 kDa

Gen-ID: 5994

NCBI Accession: NP_000529

UniProt: O00287