PHOX2A Antikörper

Produktnummer ABIN2457912

Produktdetails anti-PHOX2A Antikörper

Target: PHOX2A (Paired-Like Homeobox 2a (PHOX2A))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHOX2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PHOX2A.

Anwendungsinformationen

Applikationshinweise: PHOX2A antibody can be used for detection of PHOX2A by ELISA at 1:1562500. PHOX2A antibody can be used for detection of PHOX2A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PHOX2A antibody at -20 °C.

Details zu PHOX2A

Target: PHOX2A (Paired-Like Homeobox 2a (PHOX2A))

Andere Bezeichnung: PHOX2A (PHOX2A Produkte)

Synonyme: ARIX antikoerper, CFEOM2 antikoerper, FEOM2 antikoerper, NCAM2 antikoerper, PMX2A antikoerper, Arix antikoerper, Phox2 antikoerper, Pmx2 antikoerper, Pmx2a antikoerper, arix antikoerper, sou antikoerper, zgc:77364 antikoerper, phox2 antikoerper, xphox2a antikoerper, paired like homeobox 2a antikoerper, paired-like homeobox 2a antikoerper, paired like homeobox 2a S homeolog antikoerper, PHOX2A antikoerper, Phox2a antikoerper, phox2a antikoerper, phox2a.S antikoerper

Hintergrund: PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 30 kDa

Gen-ID: 401

NCBI Accession: NP_005160

UniProt: O14813