NLRP10 Antikörper

Produktnummer ABIN2435088

Produktdetails anti-NLRP10 Antikörper

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP10 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human NLRP10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NLRP10

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Andere Bezeichnung: NLRP10 (NLRP10 Produkte)

Synonyme: CLR11.1 antikoerper, NALP10 antikoerper, NOD8 antikoerper, PAN5 antikoerper, PYNOD antikoerper, 6430548I20Rik antikoerper, Nalp10 antikoerper, Napl10 antikoerper, Pynod antikoerper, NLR family pyrin domain containing 10 antikoerper, NLR family, pyrin domain containing 10 antikoerper, NLRP10 antikoerper, Nlrp10 antikoerper

Hintergrund: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.

Molekulargewicht: Calculated MW: 75 kDa

NCBI Accession: NP_789791

Pathways: Inflammasome