MAL Antikörper

Produktnummer ABIN2433347

Produktdetails anti-MAL Antikörper

Target: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAL Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human MAL

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MAL

Target: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Andere Bezeichnung: MAL (MAL Produkte)

Synonyme: AI326936 antikoerper, Bp50 antikoerper, GP39 antikoerper, HIGM1 antikoerper, IGM antikoerper, IMD3 antikoerper, T-BAM antikoerper, TRAP antikoerper, Tnfrsf5 antikoerper, p50 antikoerper, Mpv17 antikoerper, Vip17 antikoerper, mal antikoerper, wyatt antikoerper, MALGENE antikoerper, im:7142606 antikoerper, zgc:112003 antikoerper, mal, T-cell differentiation protein antikoerper, CD40 antigen antikoerper, myelin and lymphocyte protein, T cell differentiation protein antikoerper, myelin and lymphocyte protein antikoerper, toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog antikoerper, MAL antikoerper, Cd40 antikoerper, Mal antikoerper, LOC100135389 antikoerper, mal antikoerper, tirap.L antikoerper

Hintergrund: The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.

NCBI Accession: NP_002362

Pathways: Asymmetric Protein Localization