BRK1 Antikörper

Produktnummer ABIN2433121

Produktdetails anti-BRK1 Antikörper

Target: BRK1 (BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRK1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human BRK1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu BRK1

Target: BRK1 (BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1))

Andere Bezeichnung: BRK1 (BRK1 Produkte)

Synonyme: brk1 antikoerper, C22H3orf10 antikoerper, brick1 antikoerper, c3orf10 antikoerper, C3orf10 antikoerper, MDS027 antikoerper, hHBrk1 antikoerper, 6720456B07Rik antikoerper, AW011779 antikoerper, ATBRK1 antikoerper, BRICK1 antikoerper, HSPC300 antikoerper, T9I22.8 antikoerper, T9I22_8 antikoerper, BRICK1, SCAR/WAVE actin-nucleating complex subunit antikoerper, BRICK1, SCAR/WAVE actin nucleating complex subunit antikoerper, brick 1 antikoerper, BRICK1, SCAR/WAVE actin-nucleating complex subunit S homeolog antikoerper, BRICK1 antikoerper, brk1 antikoerper, BRK1 antikoerper, Brk1 antikoerper, brk1.S antikoerper

Hintergrund: HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton. HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization. Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex. The WAVE complex includes five proteins, one of which is HSPC300, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent. Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, it is thought to have the same or similar functions in many different organisms.

NCBI Accession: NP_060932

Pathways: RTK Signalweg