2900068C24Rik antikoerper, Ddxbp1 antikoerper, GBP antikoerper, DDXBP1 antikoerper, GU/RH-II antikoerper, ZMIZ3 antikoerper, ddxbp1 antikoerper, gbp antikoerper, pias antikoerper, pias1-A antikoerper, xPAIS1 antikoerper, xPIAS1 antikoerper, zmiz3 antikoerper, protein inhibitor of activated STAT 1 antikoerper, protein inhibitor of activated STAT, 1 antikoerper, protein inhibitor of activated STAT, 1a antikoerper, protein inhibitor of activated STAT 1 L homeolog antikoerper, PIAS1 antikoerper, Pias1 antikoerper, pias1a antikoerper, pias1.L antikoerper
Hintergrund
This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis.