PKD1 Antikörper

Produktnummer ABIN2431381

Produktdetails anti-PKD1 Antikörper

Target: PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKD1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human PKD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PKD1

Target: PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

Andere Bezeichnung: PKD1 (PKD1 Produkte)

Synonyme: PBP antikoerper, Pc-1 antikoerper, TRPP1 antikoerper, PC1 antikoerper, mFLJ00285 antikoerper, polycystin 1, transient receptor potential channel interacting antikoerper, polycystin 1, transient receptor poteintial channel interacting antikoerper, polycystin-1 antikoerper, PKD1 antikoerper, Pkd1 antikoerper, LOC749291 antikoerper

Hintergrund: This gene encodes a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis. It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. It plays a role in renal tubular development, and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1).

NCBI Accession: NP_001009944

Pathways: Myometrial Relaxation and Contraction, Maintenance of Protein Location