ANKMY2 Antikörper

Produktnummer ABIN2429175

Produktdetails anti-ANKMY2 Antikörper

Target: ANKMY2 (Ankyrin Repeat and MYND Domain Containing 2 (ANKMY2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANKMY2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human ANKMY2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ANKMY2

Target: ANKMY2 (Ankyrin Repeat and MYND Domain Containing 2 (ANKMY2))

Andere Bezeichnung: ANKMY2 (ANKMY2 Produkte)

Synonyme: ZMYND20 antikoerper, AI035571 antikoerper, Gna14 antikoerper, ankmy2 antikoerper, si:dkeyp-25a3.5 antikoerper, fi46e08 antikoerper, wu:fi46e08 antikoerper, zgc:55491 antikoerper, ankyrin repeat and MYND domain containing 2 antikoerper, ankyrin repeat and MYND domain containing 2b antikoerper, ankyrin repeat and MYND domain containing 2a antikoerper, ANKMY2 antikoerper, Ankmy2 antikoerper, ankmy2b antikoerper, ankmy2a antikoerper

Hintergrund: ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states.