Factor VII Antikörper

Produktnummer ABIN2428811

Produktdetails anti-Factor VII Antikörper

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Factor VII Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Antigen affinity purification

Immunogen: Recombinant protein of human F7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at -20°C (regular) and -80°C (long term).

Details zu Factor VII

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Andere Bezeichnung: F7 (F7 Produkte)

Synonyme: F7 antikoerper, wu:fb59f04 antikoerper, zgc:109870 antikoerper, SPCA antikoerper, AI114908 antikoerper, ATIII antikoerper, At-3 antikoerper, At3 antikoerper, LOC100223776 antikoerper, AI132620 antikoerper, Cf7 antikoerper, FVII antikoerper, mfVII antikoerper, f7 antikoerper, coagulation factor VII antikoerper, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 antikoerper, coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog antikoerper, F7 antikoerper, f7 antikoerper, Serpinc1 antikoerper, CpipJ_CPIJ009142 antikoerper, CpipJ_CPIJ010295 antikoerper, CpipJ_CPIJ020127 antikoerper, fa7 antikoerper, f7.S antikoerper

Hintergrund: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms: SPCA

Molekulargewicht: Calculated MW: 49 kDa

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling