RAB8A Antikörper

Produktnummer ABIN2425485

Produktdetails anti-RAB8A Antikörper

Target: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB8A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human RAB8A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at -20°C (regular) and -80°C (long term).

Details zu RAB8A

Target: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Andere Bezeichnung: RAB8A (RAB8A Produkte)

Synonyme: rab8A antikoerper, DDBDRAFT_0206521 antikoerper, DDBDRAFT_0214885 antikoerper, DDB_0206521 antikoerper, DDB_0214885 antikoerper, HSH2D antikoerper, mel antikoerper, rab8 antikoerper, c-mel antikoerper, MEL antikoerper, RAB8 antikoerper, zgc:162699 antikoerper, AA409338 antikoerper, Mel antikoerper, Rab8 antikoerper, rab8A protein antikoerper, Rab GTPase antikoerper, RAB8A, member RAS oncogene family antikoerper, RAB8A, member RAS oncogene family S homeolog antikoerper, rab8A antikoerper, RAB8A antikoerper, rab8a antikoerper, rab8a.S antikoerper, Rab8a antikoerper

Hintergrund: The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97 % , 96 %, and 51 % similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.
Synonyms: MEL, RAB8

Molekulargewicht: Calculated MW: 24 kDa

Pathways: M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interaktom