RGS1 Antikörper

Produktnummer ABIN2424069

Produktdetails anti-RGS1 Antikörper

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human RGS1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RGS1

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Andere Bezeichnung: RGS1 (RGS1 Produkte)

Synonyme: 1R20 antikoerper, BL34 antikoerper, IER1 antikoerper, IR20 antikoerper, RGS1 antikoerper, 1r20 antikoerper, bl34 antikoerper, ier1 antikoerper, ir20 antikoerper, regulator of G protein signaling 1 antikoerper, regulator of G-protein signaling 1 antikoerper, regulator of G-protein signaling 1 S homeolog antikoerper, Regulator of G-protein signaling 1 antikoerper, RGS1 antikoerper, Rgs1 antikoerper, rgs1.S antikoerper, rgs1 antikoerper

Hintergrund: This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Molekulargewicht: Calculated MW: 24 kDa

Pathways: MAPK Signalweg, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events