CCDC106 Antikörper

Produktnummer ABIN2423069

Produktdetails anti-CCDC106 Antikörper

Target: CCDC106 (Coiled-Coil Domain Containing 106 (CCDC106))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC106 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CCDC106

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CCDC106

Target: CCDC106 (Coiled-Coil Domain Containing 106 (CCDC106))

Andere Bezeichnung: CCDC106 (CCDC106 Produkte)

Synonyme: im:6909208 antikoerper, zgc:113396 antikoerper, HSU79303 antikoerper, ZNF581 antikoerper, BC018462 antikoerper, RGD1566222 antikoerper, coiled-coil domain containing 106b antikoerper, coiled-coil domain containing 106 antikoerper, ccdc106b antikoerper, CCDC106 antikoerper, Ccdc106 antikoerper

Hintergrund: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.