CRHR1 Antikörper (AA 107-117)
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- Target Alle CRHR1 Antikörper anzeigen
- CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
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Bindungsspezifität
- AA 107-117
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser CRHR1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Verwendungszweck
- CRHR1 / CRF-R (aa 107 - 117)
- Sequenz
- NEEKKSKVHY H
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Güteklasse
- Verified
- Immunogen
- Peptide with sequence C-NEEKKSKVHYH, from the internal region of the protein sequence according to NP_004373.2.
- Isotyp
- IgG
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- Applikationshinweise
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Western Blot: Approx 60 kDa band observed in Human Brain (Cerebellum), Colon, Rat Brain and Mouse spinal cord lysates (calculated MW of 47.7 kDa according to NP_004373.2). The observed molecular weight corresponds to earlier findings in literature with di
Peptide ELISA: antibody detection limit dilution 1:128000.
- Kommentare
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Immunofluorescence: Expression of the protein seen in the membranes, vesicles and cytoplasm of MCF7 and Neuro2a cells. Recommended concentration: 10μg/ml.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Minimize freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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Exchange protein directly activated by cAMP 2 is required for corticotropin-releasing hormone-mediated spine loss." in: The European journal of neuroscience, Vol. 50, Issue 7, pp. 3108-3114, (2020) (PubMed).
: "Activation of neuropeptide S-expressing neurons in the locus coeruleus by corticotropin-releasing factor." in: The Journal of physiology, Vol. 590, Issue Pt 16, pp. 3701-17, (2012) (PubMed).
: "Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 302, Issue 9, pp. G925-36, (2012) (PubMed).
: "
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Exchange protein directly activated by cAMP 2 is required for corticotropin-releasing hormone-mediated spine loss." in: The European journal of neuroscience, Vol. 50, Issue 7, pp. 3108-3114, (2020) (PubMed).
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- Target
- CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
- Andere Bezeichnung
- CRHR1 (CRHR1 Produkte)
- Synonyme
- CRF-R antikoerper, CRF-R-1 antikoerper, CRF-R1 antikoerper, CRF1 antikoerper, CRFR-1 antikoerper, CRFR1 antikoerper, CRH-R-1 antikoerper, CRH-R1 antikoerper, CRH-R1h antikoerper, CRHR antikoerper, CRHR1L antikoerper, CRHR1f antikoerper, Crhr antikoerper, crhr1 antikoerper, crhr1-A antikoerper, CRHR1 antikoerper, CRHR1-IT1-CRHR1 antikoerper, MGC57346-CRHR1 antikoerper, corticotropin releasing hormone receptor 1 antikoerper, corticotropin releasing hormone receptor 1, gene 2 S homeolog antikoerper, corticotropin-releasing factor receptor 1 antikoerper, LINC02210-CRHR1 readthrough antikoerper, CRHR1 antikoerper, Crhr1 antikoerper, crhr1.2.S antikoerper, LOC610380 antikoerper, LOC100065598 antikoerper, LINC02210-CRHR1 antikoerper, crhr1 antikoerper
- Hintergrund
- CRHR1, CRF-R, corticotropin releasing hormone receptor 1, CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f, corticotropin releasing hormone receptor variant 1h, seven transmembrane helix receptor
- Gen-ID
- 1394, 12921, 58959
- NCBI Accession
- NP_004373
- Pathways
- Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity
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