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PIN1 Antikörper (Internal Region)

PIN1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN233831
  • Target Alle PIN1 Antikörper anzeigen
    PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
    Bindungsspezifität
    • 15
    • 13
    • 11
    • 9
    • 8
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 109
    • 52
    • 37
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 101
    • 13
    • 2
    • 1
    Kaninchen
    Klonalität
    • 103
    • 14
    Polyklonal
    Konjugat
    • 58
    • 13
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PIN1 Antikörper ist unkonjugiert
    Applikation
    • 86
    • 48
    • 39
    • 31
    • 20
    • 19
    • 14
    • 14
    • 13
    • 13
    • 5
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Hund, Schaf, Affe
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an sequence of human Pin1.
    Isotyp
    IgG
    Top Product
    Discover our top product PIN1 Primärantikörper
  • Applikationshinweise
    This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 18 kDa in size corresponding to Pin1 by western blotting in the appropriate cell lysate or extract.  Lysates from 3T3, Jurkat, 293 or HeLa cells, as well as HeLa nuclear extract, are recommended for use as positive controls.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.2 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Lucchetti, Caligiuri, Toffoli, Giordano, Rizzolio: "The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor α in breast cancer." in: PLoS ONE, Vol. 8, Issue 2, pp. e55355, (2013) (PubMed).

    La Montagna, Caligiuri, Maranta, Lucchetti, Esposito, Paggi, Toffoli, Rizzolio, Giordano: "Androgen receptor serine 81 mediates Pin1 interaction and activity." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 18, pp. 3415-20, (2013) (PubMed).

    Rizzolio, Lucchetti, Caligiuri, Marchesi, Caputo, Klein-Szanto, Bagella, Castronovo, Giordano: "Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1." in: Cell death and differentiation, Vol. 19, Issue 7, pp. 1152-61, (2012) (PubMed).

  • Target
    PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
    Andere Bezeichnung
    PIN1 (PIN1 Produkte)
    Synonyme
    DOD antikoerper, UBL5 antikoerper, dod antikoerper, ubl5 antikoerper, pin1 antikoerper, pin1a antikoerper, 0610025L01Rik antikoerper, D9Bwg1161e antikoerper, pin1b antikoerper, zgc:73206 antikoerper, PPIase pin1 antikoerper, MdPin1 antikoerper, Pin1 antikoerper, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 antikoerper, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 S homeolog antikoerper, protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 antikoerper, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 L homeolog antikoerper, peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 antikoerper, peptidyl-prolyl cis-trans isomerase Pin1 antikoerper, PIN1 antikoerper, Pin1 antikoerper, pin1 antikoerper, pin1.S antikoerper, pin1.L antikoerper, ppiD antikoerper, PITG_11123 antikoerper, LOC103419188 antikoerper
    Hintergrund
    Pin1 (peptidylprolyl cis/trans isomerase NIMA-interacting 1 protein) is an essential peptidylprolyl isomerase that regulates mitosis, presumably by interacting with NIMA and attenuating its mitosis-promoting activity.  Pin1 displays a preference for an acidic residue N-terminal to the isomerized proline bond and also catalyzes pSer/Thr-Pro cis/trans isomerizations.  Pin1 shows a nuclear localization.
    Synonyms: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 antibody, Prolyl isomerase antibody, Protein (peptidylprolyl cis/trans isomerase) NIMA interacting 1 antibody, Protein NIMA interacting 1 antibody, Rotamase Pin1 antibody, UBL 5 antibody
    Gen-ID
    5300, 5453898
    UniProt
    Q13526
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